Searching PubMed
Searching PubMed
Always search PubMed from PCOM Library website links. The great advantage of searching via the PCOM Library web site is direct linking to fulltext articles in all PCOM licensed electronic resources. If you go directly to PubMed you will not have "Linkout" to PCOM full text.
Here is a a short video demonstrating this search.
Step 1: Use PICO to formulate the search strategy; start with the Patient problem(s) and Intervention
Enter the term for the patient problem and the intervention: obesity AND diabetes type 2 AND bariatric surgery. PubMed attempts to map your terms to appropriate Medical Subject Headings (MeSH). MeSH is the standard terminology used by the indexer and helps find articles on specific topics, regardless of the exact wording used by the authors. Indexing matters because the more in-depth the indexing, the more targeted the retrieval. The PubMed search engine will map from your free text inquiry to the controlled vocabulary so you will get the best and most comprehensive results.
Step 2. Look at Search Details to verify MeSH terms
Look in the Search Details box (lower right column; click on "See more" to expand) to see the terms that PubMed actually used in its search. You want to be sure PubMed found the appropriate MeSH terms. PubMed will automatically also search for your terms as words in the title and abstract. Obesity is a MeSH term, diabetes type 2 is translated to the MeSH term of diabetes mellitus, type 2, and bariatric surgery is a MeSH term. If your search did not find the appropriate MeSH terms, you would need to look up the topic in the MeSH database.
Step 3. Limit to appropriate study design
This is a therapy question. We know from the previous discussion that the best evidence for a therapy question is a randomized controlled clinical trial (RCT). Use the Filters column from the main results page to limit to Randomized Controlled Trial as an article type. You may need to click on "more" to see additional filters if RCT is not listed.
Use additional Limits to target retrieval.
- English
- Human
- Age
- Gender
- Date
You can also use the Clinical Queries function to limit the results to study methodologies relevant to therapy questions. Copy your last search strategy obesity AND diabetes type 2 AND bariatric surgery. Click on Advanced under the search box; then click on More Resources near the top of the page; then select Clinical Queries. Paste the search strategy in the Clinical Query search box and hit Search. The first column of results is Clinical Study Categories. Select the type of question (Therapy) and the type of search (Narrow). You may get more search results using the Clinical Queries function.
Step 4. Review the results
Both methods limit your results to RCTs. The fourth citation is of interest:
Mingrone G. Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Engl J Med. 2012 Apr 26;366(17):1577-85. doi: 10.1056/NEJMoa1200111. Epub 2012 Mar 26. PubMed PMID:22449317.
If you are not familiar with searching PubMed, review the PubMed tutorials at http://www.nlm.nih.gov/bsd/disted/pubmedtutorial/. Time spent on developing search skills is a good investment in time saving.
The next step is to read the study and determine if the methodology is sound so that we can consider the results.